Practical Surgical Neuropathology: A Diagnostic Approach

Practical Surgical Neuropathology: Foundational Principles and Diagnostic Challenges

Mini-review: Eosinophils, a Useful Diagnostic Clue in Surgical Neuropathology

Eosinophils are one of the polymorphonuclear granulocytes derived from bone marrow stem cells, and they contain many small cytoplasmic granules that stain bright red with eosin or brick-red with Romanowsky staining. Eosinophilic infiltration is also present in various human central nervous system (CNS) diseases such as parasitic infection, transverse myelitis, vasculitis, Langerhans cell histio...

A Practical Diagnostic Approach to Food Allergies

Any abnormal reaction resulting from the ingestion of a food could be considered an adverse food reaction, and not necessarily a food allergy. In the evaluation of a patient with a history of an adverse reaction to food, one must consider the broad differential diagnosis before labelling the patient as ‘allergic’ to a foodstuff. The classification of adverse reactions to food is discussed, and ...

CNS lymphoma: a practical diagnostic approach.

The concept and understanding of central nervous system (CNS) lymphoma have greatly evolved in the past few years. Better characterization of a number of lymphoproliferative neoplasms through clinical, immunophenotyping, and molecular studies is reflected in a much more complex WHO Classification of Tumours of Hematopoietic and Lymphoid Tissue. The term "primary CNS lymphoma" is now restricted ...

Zenker's Diverticulum: Diagnostic Approach and Surgical Management

Zenker's diverticulum (ZD), also known as cricopharyngeal, pharyngoesophageal or hypopharyngeal diverticulum, is a rare condition characterized by an acquired outpouching of the mucosal and submucosal layers originating from the pharyngoesophageal junction. This false and pulsion diverticulum occurs dorsally at the pharyngoesophageal wall between the inferior pharyngeal constrictor and the cric...